Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNZJAE)

Drug Name

AAV-CNGA3 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Achromatopsia	9B70	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Investigative Drug(s)

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Drug(s) Targeting Cyclic nucleotide-gated channel alpha-3 (CNGA3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ACHM-CNGA3	DMIRGTZ	Achromatopsia	9B70	Phase 1/2	[3]
L-(cis)-diltiazem	DMK07MI	Discovery agent	N.A.	Investigative	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cyclic nucleotide-gated channel alpha-3 (CNGA3)	TTW0QOV	CNGA3_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT03758404) Gene Therapy for Achromatopsia (CNGA3) (CNGA3). U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of MeiraGTx.
3	Clinical pipeline report, company report or official report of Applied Genetic Technologies.
4	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 396).