Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMO2V5C)

Drug Name

ISIS 9023 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting PKC-zeta messenger RNA (PRKCZ mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BALANOL	DMDLN9E	N. A.	N. A.	Terminated	[2]
LY-326449	DMN53M4	Discovery agent	N.A.	Investigative	[3]
Go 6983	DMKVTZN	Discovery agent	N.A.	Investigative	[4]
ISIS 9008	DMQDZF2	Discovery agent	N.A.	Investigative	[1]
ISIS 9022	DM7TRSB	Discovery agent	N.A.	Investigative	[1]
ISIS 9007	DMGK2TQ	Discovery agent	N.A.	Investigative	[1]
ISIS 9025	DMAQ7XH	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
PKC-zeta messenger RNA (PRKCZ mRNA)	TTBSN0L	KPCZ_HUMAN	Not Available	[1]

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References

1	US patent application no. 5,959,096, Antisense oligonucleotides against human protein kinase C.
2	Evaluation of differential hypoxic cytotoxicity and electrochemical studies of nitro 5-deazaflavins, Bioorg. Med. Chem. Lett. 5(18):2155-2160 (1995).
3	(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H... J Med Chem. 1996 Jul 5;39(14):2664-71.
4	Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 1996 Aug 26;392(2):77-80.