Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMO72IF)

Drug Name
AMG 301 Drug Info
Indication
Disease Entry ICD 11 Status REF
Migraine 8A80 Phase 2 [1]
Hyperprolactinaemia 5A60.1 Investigative [2]
Cross-matching ID
TTD Drug ID
DMO72IF

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting PACAP type I receptor (PAC1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PACAP-27 DMB26IK Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
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Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PACAP type I receptor (PAC1R) TT5OREU PACR_HUMAN Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 PACAP38 and PAC1 receptor blockade: a new target for headache J Headache Pain. 2018 Aug 7;19(1):64.
3 A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology. Neuropharmacology. 2006 Nov;51(6):1086-98.