Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMO84TL)

Drug Name
ME-3407 Drug Info
Synonyms EF-4040; 2-(Butoxycarbonylmethylsulfinyl)thiazolo[5,4-b]pyridine; 2-(Thiazolo[5,4-b]pyridin-2-ylsulfinyl)acetic acid butyl ester
Indication
Disease Entry ICD 11 Status REF
Duodenal ulcer DA63 Phase 2 [1]
Cross-matching ID
PubChem CID
6918179
TTD Drug ID
DMO84TL

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Myosin light kinase (MYLK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RKI-1447 DMGTAWC Discovery agent N.A. Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Myosin light kinase (MYLK) TT18ETS MYLK_HUMAN Inhibitor [1]

References

1 ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H(+)-K(+)-ATPase. Am J Physiol. 1997 May;272(5 Pt 1):G1122-34.
2 Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709.