Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOXDIY)

Drug Name
CB-5339 Drug Info
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 1 [1]
Myelodysplastic syndrome 2A37 Phase 1 [1]
Cross-matching ID
PubChem CID
122685543
TTD Drug ID
DMOXDIY

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Valosin-containing protein p97 (VCP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CB-5083 DM12GN7 Multiple myeloma 2A83 Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Valosin-containing protein p97 (VCP) TTHNLSB TERA_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT04402541) Study of CB-5339 in Acute Myeloid Leukemia or Myelodysplastic Syndrome. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Cleave Therapeutics.
3 Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC Cancer. 2015; 15: 479.