Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOZW4C)

Drug Name
Neublastin Drug Info
Indication
Disease Entry ICD 11 Status REF
Pain MG30-MG3Z Phase 2 [1]
Cross-matching ID
TTD Drug ID
DMOZW4C

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
GDNF receptor alpha-3 (GFRA3) TT63XRS GFRA3_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT01873404) BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy. U.S. National Institutes of Health.
2 First-In-Human, Double-Blind, Placebo-Controlled, Randomized, Dose-Escalation Study of BG00010, a Glial Cell Line-Derived Neurotrophic Factor Family Member, in Subjects with Unilateral Sciatica. PLoSOne. 2015 May 11;10(5):e0125034.