Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPB9OD)

Drug Name

OBI-999 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Globohexaosylceramide (Globo H)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
OBI-888	DMD2L1U	Solid tumour/cancer	2A00-2F9Z	Phase 1/2	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Globohexaosylceramide (Globo H)	TT4UXTG	NOUNIPROTAC	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT04084366) Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
2	Preclinical Studies of OBI-999: A Novel Globo H-Targeting Antibody-Drug Conjugate. Mol Cancer Ther. 2021 Jun;20(6):1121-1132.
3	Clinical pipeline report, company report or official report of OBI Pharma.