General Information of Drug (ID: DMPDVM8)

Drug Name
ABT-510 Drug Info
Synonyms N-Acetyl-N-methyl-glycyl-glycyl-L-valyl-D-alloisoleucyl-L-threonyl-L-norvalyl-L-isoleucyl-L-argininyl-L-proline N-ethylamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Cross-matching ID
PubChem CID
6918562
CAS Number
CAS 251579-55-2
TTD Drug ID
DMPDVM8

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Drug(s) Targeting Thrombospondin-1 (THBS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
CVX-045 DMCN9GX Solid tumour/cancer 2A00-2F9Z Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thrombospondin-1 (THBS1) TTKI0H1 TSP1_HUMAN Modulator [2]

References

1 ClinicalTrials.gov (NCT00602199) ABT-510 in Treating Patients With Metastatic Melanoma. U.S. National Institutes of Health.
2 A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma. Am J Clin Oncol. 2007 Jun;30(3):303-9.
3 Antitumor efficacy of a thrombospondin 1 mimetic CovX-body. Transl Oncol. 2011 Aug;4(4):249-57.