Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPFX0S)

Drug Name
5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Drug Info
Synonyms 5-(dimethylamino)naphthalene-2-sulfonic acid; AC1NBV3O; 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID; SCHEMBL18300795; DB07684; 5-dimethyl-aminonaphthalene-2-sulfonic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
4474224
TTD Drug ID
DMPFX0S

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Tissue-type plasminogen activator (PLAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aminocaproic Acid DMFGND4 Bleeding disorder GA20-GA21 Approved [2]
2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine DM3UMYD Discovery agent N.A. Investigative [3]
1-guanidino-N-phenyl-7-isoquinolinesulphonamide DMTF1HL Discovery agent N.A. Investigative [4]
BMS-344577 DM9WRUG Discovery agent N.A. Investigative [5]
N-(4-Chloro-7-p-tolyl-isoquinolin-1-yl)-guanidine DMNO46U Discovery agent N.A. Investigative [6]
N-(4-Phenyl-pyridin-2-yl)-guanidine DMYD4PC Discovery agent N.A. Investigative [7]
N-(7-Benzyloxy-isoquinolin-1-yl)-guanidine DMPMBC2 Discovery agent N.A. Investigative [6]
N-(5-Benzyloxy-isoquinolin-1-yl)-guanidine DMGAITY Discovery agent N.A. Investigative [6]
⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tissue-type plasminogen activator (PLAT) TTXAGYU TPA_HUMAN Inhibitor [1]

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3 Development of serine protease inhibitors displaying a multicentered short (<2.3 A) hydrogen bond binding mode: inhibitors of urokinase-type plasmi... J Med Chem. 2001 Aug 16;44(17):2753-71.
4 Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. J Med Chem. 2007 May 17;50(10):2341-51.
5 Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6882-9.
6 Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 3: 1-isoquinolinylguanidines. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3227-30.
7 Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. Bioorg Med Chem Lett. 2002 Jan 21;12(2):181-4.