Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPGIWT)

Drug Name

TB47 Drug Info

Synonyms

CHEMBL3612958; 1799682-71-5; 5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide; 5-Methoxy-2-methyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl)pyrazolo[1,5-a]pyridine-3-carboxamide; TB47; SCHEMBL19514093; HQECXZKIRDUGLC-UHFFFAOYSA-N; BDBM50598091; 5-methoxy-2-methyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidyl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide; HV0

Indication

Disease Entry	ICD 11	Status	REF
Tuberculosis	1B10-1B14	Preclinical	[1]

Cross-matching ID

PubChem CID: 122188597
TTD Drug ID: DMPGIWT

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Cytochrome bc1 complex cytochrome b subunit (qcrB)	TT07X7W	QCRB_MYCTU	Inhibitor	[2]

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References

1	The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0096421.
2	The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0096421.