Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPNQ27)

Drug Name
Il-94 Drug Info
Synonyms CHEMBL2386715; Il-94; GTPL8132; SCHEMBL15216595; BDBM50434330
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
73348907
TTD Drug ID
DMPNQ27

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting PAK-1 protein kinase (PAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
RKI-1447 DMGTAWC Discovery agent N.A. Investigative [2]
PMID20005102C1 DMMESBW Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PAK-1 protein kinase (PAK1) TTFN95D PAK1_HUMAN Inhibitor [1]
PAK-2 protein kinase (PAK2) TT279WO PAK2_HUMAN Inhibitor [1]

References

1 PAK1: A Therapeutic Target for Cancer Treatment. ACS Med Chem Lett. 2013 Mar 19;4(5):431-2.
2 Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2). Medchemcomm. 2012 Jun 1;3(6):699-709.
3 2,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles. Bioorg Med Chem Lett. 2010 Jan 15;20(2):679-83.