Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPO4M1)

Drug Name
Paquinimod Drug Info
Synonyms ABR-215757; ABR-25757; Project 57-57, Active Biotech
Indication
Disease Entry ICD 11 Status REF
Lupus 4A40 Phase 2 [1]
Cross-matching ID
PubChem CID
54684617
CAS Number
CAS 248282-01-1
TTD Drug ID
DMPO4M1

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Calgranulin B (S100A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tasquinimod DM9GSVQ Prostate cancer 2C82.0 Phase 3 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calgranulin B (S100A9) TT0TMQG S10A9_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT01487551) An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod). U.S. National Institutes of Health.
2 Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis. Ann Rheum Dis. 2015 Dec;74(12):2254-8.
3 Mechanisms of action of tasquinimod on the tumour microenvironment. Cancer Chemother Pharmacol. 2014; 73(1): 1-8.