Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPWOH9)

Drug Name

DKY709 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Zinc finger protein Helios (IKZF2)	TTKT5NV	IKZF2_HUMAN	Degrader	[2]

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References

1	ClinicalTrials.gov (NCT03891953) Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.. U.S. National Institutes of Health.
2	Targeted protein degraders crowd into the clinic. Nat Rev Drug Discov. 2021 Apr;20(4):247-250.