Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPXDL6)

Drug Name

ABBV-CLS-579 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosine-protein phosphatase non-receptor type 2 (PTPN2)	TTY8PUS	PTN2_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04417465) First In Human Study With ABBV-CLS-579 When Given Alone Or In Combination With Programmed Cell Death-1 Inhibitor In Participants With Locally Advanced Or Metastatic Tumors. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of Calico Life Sciences.