Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMPYIA3)

Drug Name
GNF-PF-4453 Drug Info
Synonyms
GNF-Pf-4453; TCMDC-125689; 4-{[3-(3,5-dimethylpiperidin-1-yl)propyl]amino}-N-(3-methoxyphenyl)-3-nitrobenzamide; MLS000689410; CHEMBL579424; MolPort-007-928-102; HMS2706G13; AKOS021653715; AKOS002143414; MCULE-1668730596; SMR000311209; SR-01000581321
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
16194189
TTD Drug ID
DMPYIA3

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Calpain-2 (CAPN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABT-957 DMB9N4J Alzheimer disease 8A20 Phase 1 [2]
PMID25399719-Compound-17 DMRXKJZ N. A. N. A. Patented [3]
Epoxysuccinate derivative 9 DM49FU0 N. A. N. A. Patented [3]
Epoxysuccinate derivative 4 DMCF6M8 N. A. N. A. Patented [3]
Carboxamide derivative 7 DM8TQS4 N. A. N. A. Patented [3]
Epoxysuccinate derivative 7 DMTSPVF N. A. N. A. Patented [3]
Carboxamide derivative 10 DM5WMO9 N. A. N. A. Patented [3]
Carboxamide derivative 11 DM1DN94 N. A. N. A. Patented [3]
Carboxamide derivative 8 DM6HI34 N. A. N. A. Patented [3]
Epoxysuccinate derivative 10 DMYF39U N. A. N. A. Patented [3]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calpain-2 (CAPN2) TTG5QB7 CAN2_HUMAN Inhibitor [1]

References

1 In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.