Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQDZF2)

Drug Name

ISIS 9008 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Targeting PKC-zeta messenger RNA (PRKCZ mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
BALANOL	DMDLN9E	N. A.	N. A.	Terminated	[2]
LY-326449	DMN53M4	Discovery agent	N.A.	Investigative	[3]
Go 6983	DMKVTZN	Discovery agent	N.A.	Investigative	[4]
ISIS 9022	DM7TRSB	Discovery agent	N.A.	Investigative	[1]
ISIS 9023	DMO2V5C	Discovery agent	N.A.	Investigative	[1]
ISIS 9007	DMGK2TQ	Discovery agent	N.A.	Investigative	[1]
ISIS 9025	DMAQ7XH	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
PKC-zeta messenger RNA (PRKCZ mRNA)	TTBSN0L	KPCZ_HUMAN	Not Available	[1]

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References

1	US patent application no. 5,959,096, Antisense oligonucleotides against human protein kinase C.
2	Evaluation of differential hypoxic cytotoxicity and electrochemical studies of nitro 5-deazaflavins, Bioorg. Med. Chem. Lett. 5(18):2155-2160 (1995).
3	(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H... J Med Chem. 1996 Jul 5;39(14):2664-71.
4	Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 1996 Aug 26;392(2):77-80.