Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQG2EY)

• Drug Name: Virstatin Drug Info
• Synonyms: 88909-96-0; Isodibut; 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid; 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid; 4-NAPHTHALIMIDOBUTYRIC ACID; 4-(N-(1,8-naphthalimide))-n-butyric acid; 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid; UNII-24SR2Q1Y6M; 24SR2Q1Y6M; MFCD00181400; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid; 1,3-dioxo-1H-Benz[de]isoquinoline-2(3H)-butanoic acid; 4-{2,4-dioxo-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaen-3-yl}butanoic acid; Izodibut; 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butyric acid; ACMC-209qxu; SpecPlus_000928; Spectrum2_000449; Spectrum3_001240; CBMicro_014897; CBKinase1_000229; CBKinase1_012629; BSPBio_002720; CBDivE_001858; CBDivE_003272; MLS001207259; DivK1c_007024; SPBio_000498; CHEMBL403272; SCHEMBL3134908; SCHEMBL3852274; KBio1_001968; KBio3_002220; 1H-Benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-dioxo-; DTXSID10237406; ZINC3884670; ANW-39184; CCG-39963; KM2782; SBB043186; STK395003; AKOS000114634; DG-0077; MCULE-6695567974; NCGC00178507-01; SMR000504925; FT-0734904; ST50049126; X6840; EN300-00247; AB00053241-05; BRD-K60241851-001-02-8; BRD-K60241851-001-06-9; Z56891243; 1h,3H-benzo(de)isoquinoline-2-butyric acid-1,3-dione; F0303-0081; 4-{2,4-Dioxo-3-azatricyclo[7.3.1.0 {5,13}]trideca- 1(13),5,7,9,11-pentaen-3-yl}butanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Acinetobacter baumannii infection	CA40.0Y	Preclinical	[1]

• Cross-matching ID:
  PubChem CID: 145949
  CAS Number: CAS 88909-96-0
  TTD Drug ID: DMQG2EY

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Vibrio TCP pilus virulence regulatory protein (Vibrio tcpN)	TTVFR2S	TCPN_VIBCH	Inhibitor	[2]

References

• [1] Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance. Nat Rev Drug Discov. 2017 Jul;16(7):457-471.
• [2] Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2372-7.