Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQRKXP)

Drug Name

AEA-35p Drug Info

Synonyms

Peptide vaccines (H1N1 influenza virus infection), Antigen Express

Indication

Disease Entry	ICD 11	Status	REF
Influenza virus infection	1E30-1E32	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting MHC class II antigen DR (HLA-DR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Apolizumab	DMKVP7E	Solid tumour/cancer	2A00-2F9Z	Phase 2	[3]
IMMU-114	DMTFUM4	Haematological malignancy	2B33.Y	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MHC class II antigen DR (HLA-DR)	TTYA75N	DRA_HUMAN; 2B1F_HUMAN; DRB3_HUMAN; DRB4_HUMAN; DRB5_HUMAN	Not Available	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035645)
2	WO patent application no. 2013,1850,32, Nanotherapeutics for drug targeting.
3	A humanized HLA-DR antibody (hu1D10, apolizumab) in combination with granulocyte colony-stimulating factor (filgrastim) for the treatment of non-Hodgkin's lymphoma: a pilot study.
4	The humanized anti-HLA-DR moAb, IMMU-114, depletes APCs and reduces alloreactive T cells: implications for preventing GVHD. Bone Marrow Transplant. 2012 Jul;47(7):967-80.