Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR0CNQ)

Drug Name

Calpastatin Drug Info

Synonyms

Acacetin-7-O-glucuronide methyl ester; AC1NUQS7; 79076-87-2; beta-D-Glucopyranosiduronic acid, 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, methyl ester; methyl (2S,3S,4S,5R)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1] , [2]

Cross-matching ID

PubChem CID: 90488788
ChEBI ID: CHEBI:131884
CAS Number: CAS 79079-11-1
TTD Drug ID: DMR0CNQ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Calpain-2 (CAPN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABT-957	DMB9N4J	Alzheimer disease	8A20	Phase 1	[3]
PMID25399719-Compound-17	DMRXKJZ	N. A.	N. A.	Patented	[4]
Epoxysuccinate derivative 9	DM49FU0	N. A.	N. A.	Patented	[4]
Epoxysuccinate derivative 4	DMCF6M8	N. A.	N. A.	Patented	[4]
Carboxamide derivative 7	DM8TQS4	N. A.	N. A.	Patented	[4]
Epoxysuccinate derivative 7	DMTSPVF	N. A.	N. A.	Patented	[4]
Carboxamide derivative 10	DM5WMO9	N. A.	N. A.	Patented	[4]
Carboxamide derivative 11	DM1DN94	N. A.	N. A.	Patented	[4]
Carboxamide derivative 8	DM6HI34	N. A.	N. A.	Patented	[4]
Epoxysuccinate derivative 10	DMYF39U	N. A.	N. A.	Patented	[4]
------------------------------------------------------------------------------------


⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calpain-2 (CAPN2)	TTG5QB7	CAN2_HUMAN	Inhibitor	[1] , [2]

------------------------------------------------------------------------------------

References

1	Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors. Brain Res Brain Res Rev. 2003 May;42(2):169-85.
2	PEST sequences in the malaria parasite Plasmodium falciparum: a genomic study. Malar J. 2003 Jun 23;2:16.
3	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
4	An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.