Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR0CNQ)

Drug Name

Calpastatin Drug Info

Synonyms

Acacetin-7-O-glucuronide methyl ester; AC1NUQS7; 79076-87-2; beta-D-Glucopyranosiduronic acid, 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, methyl ester; methyl (2S,3S,4S,5R)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-methoxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylate

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 90488788
ChEBI ID: CHEBI:131884
CAS Number: CAS 79079-11-1
TTD Drug ID: DMR0CNQ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Patented Agent(s)

Download the Complete Related Drug List

Drug(s) Targeting Calpain-2 (CAPN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABT-957	DMB9N4J	Alzheimer disease	8A20	Phase 1	[2]
PMID25399719-Compound-17	DMRXKJZ	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 9	DM49FU0	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 4	DMCF6M8	N. A.	N. A.	Patented	[3]
Carboxamide derivative 7	DM8TQS4	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 7	DMTSPVF	N. A.	N. A.	Patented	[3]
Carboxamide derivative 10	DM5WMO9	N. A.	N. A.	Patented	[3]
Carboxamide derivative 11	DM1DN94	N. A.	N. A.	Patented	[3]
Carboxamide derivative 8	DM6HI34	N. A.	N. A.	Patented	[3]
Epoxysuccinate derivative 10	DMYF39U	N. A.	N. A.	Patented	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Calpain-2 (CAPN2)	TTG5QB7	CAN2_HUMAN	Inhibitor	[1]

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References

1	Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors. Brain Res Brain Res Rev. 2003 May;42(2):169-85.
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	An updated patent review of calpain inhibitors (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):17-31.