Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR0K85)

Drug Name

RX-77368 Drug Info

Synonyms

TRH analog, Reckitt & Colman

Indication

Disease Entry	ICD 11	Status	REF
Dementia	6D80-6D86	Discontinued in Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Thyrotropin-releasing hormone (TRH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
KPS-0373	DMP5G1K	Parkinson disease	8A00.0	Phase 3	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thyrotropin-releasing hormone (TRH)	TT2Z39D	TRH_HUMAN	Modulator	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001316)
2	Intracisternal urocortin inhibits vagally stimulated gastric motility in rats: role of CRF(2).Br J Pharmacol.2002 May;136(2):237-47.
3	DOI: 10.1002/mdc3.12057