Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMR3Z49)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Tyrosine-protein kinase EIF2AK2 (p68)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9650366, 2	DM9HZ03	N. A.	N. A.	Patented	[1]
US9650366, 9	DMUCIPE	N. A.	N. A.	Patented	[1]
NU6140	DMCUSG3	Discovery agent	N.A.	Investigative	[2]
ASN-11124542	DMFNZOI	Discovery agent	N.A.	Investigative	[3]
indirubin derivative E804	DMFP1C5	Discovery agent	N.A.	Investigative	[2]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tyrosine-protein kinase EIF2AK2 (p68)	TTXEZJ4	E2AK2_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366.
2	Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.
3	Small molecule inhibitors of the RNA-dependent protein kinase. Biochem Biophys Res Commun. 2003 Aug 15;308(1):50-7.