Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRAWGC)

Drug Name
KM-819 Drug Info
Indication
Disease Entry ICD 11 Status REF
Parkinson disease 8A00.0 Phase 1 [1]
Cross-matching ID
PubChem CID
25009726
TTD Drug ID
DMRAWGC

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
FAS-associated factor 1 (FAF1) TTSKL3G FAF1_HUMAN Inhibitor [2]

References

1 ClinicalTrials.gov (NCT03022799) Phase I, KM-819 in Healthy Subjects for Parkinson's Disease. U.S. National Institutes of Health.
2 A first-in-human study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of KM-819 (FAS-associated factor 1 inhibitor), a drug for Parkinson's disease, in healthy volunteers. Drug Des Devel Ther. 2019 Mar 29;13:1011-1022.