Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRCMEK)

Drug Name

BMS-PCSK9 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Coronary artery disease	BA80	Preclinical	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Preclinical Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting PCSK9 messenger RNA (PCSK9 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Inclisiran	DMP3YTE	Familial hypercholesterolemia	5C80.00	Approved	[2]
MPSK3169A	DMMRYEK	Cardiovascular disease	BA00-BE2Z	Phase 2	[3]
AZD8233	DMBT2D2	Cardiovascular disease	BA00-BE2Z	Phase 2	[4]
ALN-PCS	DMCJMOS	Hypercholesterolaemia	5C80.0	Preclinical	[5]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
2	FDA Approved Drug Products from FDA Official Website. 2021. Application Number: 214012.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2388).
4	AZD8233 antisense oligonucleotide targeting PCSK9 does not prolong QT interval. Br J Clin Pharmacol. 2022 Nov;88(11):4839-4844.
5	Clinical pipeline report, company report or official report of Alnylam Pharmaceuticals, Inc (2011).