Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRDY0G)

Drug Name

ACV-1 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Neuropathic pain	8E43.0	Phase 1	[1]

Therapeutic Class

Analgesics

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Neuronal acetylcholine receptor alpha-10 (CHRNA10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
[3H]methyllycaconitine	DMYWGCS	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Neuronal acetylcholine receptor alpha-10 (CHRNA10)	TTJ49OM	ACH10_HUMAN	Modulator	[2]

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References

1	Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.
2	Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 470).