Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRK4FA)

Drug Name

N-(2-aminoethyl)-1-aziridine-ethanamine Drug Info

Synonyms

NAAE; N-(2-aminoethyl)-1-aziridineethanamine

Indication

Disease Entry	ICD 11	Status	REF
Severe acute respiratory syndrome (SARS)	1D65	Investigative	[1]

Therapeutic Class

Antiviral Agents

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

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Drug(s) Targeting HUMAN angiotensin-converting enzyme 2 (ACE2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
rhACE2	DMBSXR9	Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2 Trial	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HUMAN angiotensin-converting enzyme 2 (ACE2)	TTYRG7F	ACE2_HUMAN	Inhibitor	[1]

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References

1	Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
2	ClinicalTrials.gov (NCT04287686) Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19