Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSRVXO)

Drug Name

BMS-986263 Drug Info

Synonyms

ND L02 s0201

Indication

Disease Entry	ICD 11	Status	REF
Hepatic fibrosis	DB93.0	Phase 2	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
SERPINH1 messenger RNA (SERPINH1 mRNA)	TTPSWQG	SERPH_HUMAN	Inhibitor	[2]

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References

1	ClinicalTrials.gov (NCT04267393) Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH). U.S. National Institutes of Health.
2	A Fit-for-Purpose Method for the Detection of Human Antibodies to Surface-Exposed Components of BMS-986263, a Lipid Nanoparticle-Based Drug Product Containing a siRNA Drug Substance. AAPS J. 2019 Jul 22;21(5):92.