Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTLYDS)

Drug Name

2-hydroxyisoquinoline-1,3(2H,4H)-dione Drug Info

Synonyms

2-hydroxyisoquinoline-1,3(2H,4H)-dione; 6890-08-0; CHEMBL16755; 2-Hydroxy-4H-isoquinoline-1,3-dione; 1,3(2H,4H)-Isoquinolinedione, 2-hydroxy-; 2-hydroxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione; 0N7; AC1LAHYL; N-hydroxyisoquinolinedione, 2; SCHEMBL3358267; BDBM33410; DTXSID70333610; ZINC3626195; 0637AC; AKOS016011468; FCH1154656; ACN-049309; AJ-45130; 2-Hydroxy-1,3(2H,4H)-isoquinolinedione; KB-230940; AX8246098

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 514100
CAS Number: CAS 6890-08-0
TTD Drug ID: DMTLYDS

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Human immunodeficiency virus Ribonuclease H (HIV RNH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
3-hydroxyquinazoline-2,4(1H,3H)-dione	DMCXZ9L	Discovery agent	N.A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Human immunodeficiency virus Ribonuclease H (HIV RNH)	TT37KAF	POL_HV1B1	Inhibitor	[1]

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References

1	RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J Med Chem. 2009 Oct 8;52(19):5781-4.