Details of the Drug-Related molecule(s) Interaction Atlas

Methylamine Drug Info

Aminomethane; Anhydrous Methylamine; BAVYZALUXZFZLV-UHFFFAOYSA-N; Carbinamine; METHYLAMINE; Mercurialin; Methanamine; Methylamine aq; Methylamine solutions; Methylamine, anhydrous; Methylamine, in aqueous solution; Methylaminen; Methylaminen [Dutch]; Metilamine; Metilamine [Italian]; Metyloamina; Metyloamina [Polish]; Monomethylamine; N-Methylamine; UN1061; UN1235; methyl-amine; monomethyl amine; 74-89-5; AI3-15637-X; BSF23SJ79E; CCRIS 2508; CH3NH2; CHEBI:16830; EINECS 200-820-0; HSDB 810; MeNH2; UNII-BSF23SJ79E

Cross-matching ID

PubChem CID

6329

ChEBI ID

CHEBI:16830

CAS Number

CAS 74-89-5

TTD Drug ID

DMTPL4W

INTEDE Drug ID

DR2042

General Information of Drug (ID: DMTPL4W)

Molecule-Related Drug Atlas

Molecule Type:

DME

Drug Status:

Discontinued Drug(s)

Investigative Drug(s)

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Drug(s) Metabolized By Copper amine oxidase (AOC3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tresperimus	DMOVBSF	Autoimmune diabetes	5A10	Discontinued in Phase 3	[2]
tyramine	DM4UXT1	Discovery agent	N.A.	Investigative	[1]
PHENETHYLAMINE	DMX0G4F	Discovery agent	N.A.	Investigative	[1]
Benzylamine	DMRM6ES	N. A.	N. A.	Investigative	[1]
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Drug(s) Metabolized By Semicarbazide-sensitive amine oxidase (AOC2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
tyramine	DM4UXT1	Discovery agent	N.A.	Investigative	[1]
PHENETHYLAMINE	DMX0G4F	Discovery agent	N.A.	Investigative	[1]
Benzylamine	DMRM6ES	N. A.	N. A.	Investigative	[1]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Copper amine oxidase (AOC3)	DE6SOC5	AOC3_HUMAN	Substrate	[1]
Semicarbazide-sensitive amine oxidase (AOC2)	DE8DP90	AOC2_HUMAN	Substrate	[1]

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References

1	The unique substrate specificity of human AOC2, a semicarbazide-sensitive amine oxidase. Cell Mol Life Sci. 2009 Aug;66(16):2743-57.
2	Metabolism of tresperimus by rat aorta semicarbazide-sensitive amine oxidase (SSAO). Fundam Clin Pharmacol. 2002 Dec;16(6):461-70.