General Information of Drug (ID: DMTUKZH)

Drug Name
Deferoxamine Mesylate Drug Info
Synonyms Desferal
Indication
Disease Entry ICD 11 Status REF
Acute iron or aluminum toxicity FB83.20 Approved [1]
Cross-matching ID
PubChem CID
62881
ChEBI ID
CHEBI:31460
CAS Number
CAS 138-14-7
TTD Drug ID
DMTUKZH
ACDINA Drug ID
D00991

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Iron (Fe)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etidronate Disodium DMAWJIN Osteoporosis FB83.0 Approved [2]
Deferiprone DMS2M7O Beta thalassemia 3A50.2 Approved [3]
Exjade DMHPRWG Iron overload disease 5C64.10 Approved [4]
Soluble ferric pyrophosphate DMLAYTP Iron-deficiency anemia 3A00 Phase 3 [5]
SPD602 DMKJ9LU Anemia 3A00-3A9Z Phase 2 [6]
Monohydroxyethylrutoside DMAQJHO Cardiovascular disease BA00-BE2Z Phase 1 [7]
DpC DM4ZDOE Solid tumour/cancer 2A00-2F9Z Phase 1 [8]
⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Iron (Fe) TTUDR0C NOUNIPROTAC Modulator [2]

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3 2011 FDA drug approvals. Nat Rev Drug Discov. 2012 Feb 1;11(2):91-4.
4 Deferasirox : a review of its use in the management of transfusional chronic iron overload. Drugs. 2007;67(15):2211-30.
5 A micronised, dispersible ferric pyrophosphate with high relative bioavailability in man. Br J Nutr. 2004 Jan;91(1):107-12.
6 ClinicalTrials.gov (NCT01604941) Pharmacokinetics of SSP-004184 in the Treatment of Chronic Iron Overload Requiring Chelation Therapy. U.S. National Institutes of Health.
7 Monohydroxyethylrutoside, a dose-dependent cardioprotective agent, does not affect the antitumor activity of doxorubicin. Clin Cancer Res. 1997 Oct;3(10):1747-54.
8 Anticancer Thiosemicarbazones: Chemical Properties, Interaction with Iron Metabolism, and Resistance Development. Antioxid Redox Signal. 2019 Mar 10;30(8):1062-1082.