Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU4CS8)

Drug Name
MEDI6012 Drug Info
Synonyms RhLCAT; ACP-501
Indication
Disease Entry ICD 11 Status REF
Coronary artery disease BA80 Phase 2 [1]
Acute coronary syndrome BA41 Phase 1 [2]
Cross-matching ID
TTD Drug ID
DMU4CS8

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lecithin-cholesterol acyltransferase (LCAT) TTGZ91P LCAT_HUMAN Modulator [3]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 ClinicalTrials.gov (NCT01554800) Effect of ACP-501 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Subjects With Coronary Artery Disease. U.S. National Institutes of Health.
3 Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria. J Nephropathol. 2015 January; 4(1): 25-28.