General Information of Drug (ID: DMU67HD)

Drug Name
ATR-01 Drug Info
Indication
Disease Entry ICD 11 Status REF
Adrenocortical carcinoma 2D11.Z Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMU67HD

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID25470667-Compound-K-604 DMYZ2UA N. A. N. A. Patented [2]
Benoxaprofen DM5ZOX8 Inflammation 1A00-CA43.1 Withdrawn from market [3]
PMID16242323C18a DMI5WPQ Discovery agent N.A. Investigative [4]
PMID16242323C16 DM2Q79X Discovery agent N.A. Investigative [4]
PMID16242323C22c DMFDRMH Discovery agent N.A. Investigative [4]
PMID16242323C26a DMD0Q7K Discovery agent N.A. Investigative [4]
Nonanoic acid biphenyl-2-ylamide DM951PF Discovery agent N.A. Investigative [5]
Octanoic acid biphenyl-2-ylamide DM4RGCX Discovery agent N.A. Investigative [5]
PMID16242323C22d DMJICNL Discovery agent N.A. Investigative [4]
PMID16242323C15a DMM4A7P Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetoacetyl-CoA thiolase (ACAT1) TTK3C21 THIL_HUMAN Inhibitor [1]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58.
3 Inhibition of lyso-PAF: acetyl-CoA acetyltransferase by salicylates and other compounds. Prostaglandins. 1988 Jun;35(6):939-44.
4 Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor wit... Bioorg Med Chem Lett. 2006 Jan 1;16(1):44-8.
5 Biphenyl versus phenylpyridazine derivatives: the role of the heterocycle in a series of acyl-CoA:cholesterol acyl transferase inhibitors. J Med Chem. 2008 Mar 13;51(5):1474-7.