Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU87HW)

Drug Name
RGX-111 Drug Info
Indication
Disease Entry ICD 11 Status REF
Mucopolysaccharidosis 5C56.3 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMU87HW

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Alpha-L-iduronidase (IDUA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SB-318 DMA8Z4N Mucopolysaccharidosis 5C56.3 Phase 1/2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Alpha-L-iduronidase (IDUA) TT0IUKX IDUA_HUMAN Replacement [2]

References

1 ClinicalTrials.gov (NCT03580083) RGX-111 Gene Therapy in Patients With MPS I. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of REGENXBIO.
3 ClinicalTrials.gov (NCT02702115) Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-318 in Subjects With MPS I. U.S. National Institutes of Health.