Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU93NS)

Drug Name

MK-5684 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Phase 1/2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Cholesterol desmolase (CYP11A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aminoglutethimide	DMWFHMZ	Cushing disease	5A70	Approved	[3]
3-(4-Amino-phenyl)-3-pentyl-piperidine-2,6-dione	DM20DXS	Discovery agent	N.A.	Investigative	[4]
3-(4-Amino-phenyl)-3-butyl-piperidine-2,6-dione	DMD5YKO	Discovery agent	N.A.	Investigative	[4]
------------------------------------------------------------------------------------

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

References

1	ClinicalTrials.gov (NCT03436485) Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Merck
3	Breakdown of Th cell immune responses and steroidogenic CYP11A1 expression in CD4+ T cells in a murine model implanted with B16 melanoma. Cell Immunol. 2000 Nov 25;206(1):7-15.
4	Aromatase inhibitors. Synthesis and evaluation of mammary tumor inhibiting activity of 3-alkylated 3-(4-aminophenyl)piperidine-2,6-diones. J Med Chem. 1986 Aug;29(8):1362-9.