Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUJ0EL)

Drug Name

BIIB132 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Spinocerebellar ataxia type 3	8A03.16	Phase 1	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting Ataxin-3 messenger RNA (ATXN3 mRNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ION260	DMR2RFL	Spinocerebellar ataxia type 3	8A03.16	Phase 1	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ataxin-3 messenger RNA (ATXN3 mRNA)	TT6A17J	ATX3_HUMAN	Not Available	[1]

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References

1	ClinicalTrials.gov (NCT05160558) A Phase 1, Blinded, Randomized, Placebo-controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of BIIB132 Administered Intrathecally to Adults With Spinocerebellar Ataxia 3. U.S.National Institutes of Health.
2	Clinical pipeline report, company report or official report of Ionis