Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUM3CP)

Drug Name
15(S)-hydroxyeicosatetraenoic acid (ophthalmic, dry eye), Alcon Drug Info
Synonyms PROCALYX; 15(S)-HETE; 15(S)-Hydroxyeicosatetraenoic acid
Indication
Disease Entry ICD 11 Status REF
Ocular disease 1F00.1Z Discontinued in Phase 3 [1]
Cross-matching ID
PubChem CID
5280724
ChEBI ID
CHEBI:15558
CAS Number
CAS 54845-95-3
TTD Drug ID
DMUM3CP

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Mucin (MUC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
KLS-0611 DM05TBE Xerophthalmia 5B55.Y Phase 2 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Mucin (MUC) TTHBUXE NOUNIPROTAC Modulator [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3401).
2 15(S)-hydroxyeicosatetraenoic acid (15-HETE), a product of arachidonic acid peroxidation, is an active component of hemozoin toxicity to monocytes. Parassitologia. 1999 Sep;41(1-3):199-202.
3 WO patent application no. 2011,1034,23, Cyclobutane and methylcyclobutane derivatives as janus kinase inhibitors.