Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMURO94)

Drug Name

GNE Lipoplex Drug Info

Synonyms

GNE Lipoplex (intramuscular, HIBM-2)

Indication

Disease Entry	ICD 11	Status	REF
Myopathy	8C7Y	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
N-acetylmannosamine kinase (GNE)	TT4DP5S	GLCNE_HUMAN	Inhibitor	[2]

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034673)
2	Hereditary inclusion body myopathy: single patient response to intravenous dosing of GNE gene lipoplex. Hum Gene Ther. 2011 Nov;22(11):1331-41.