Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUTDNV)

• Drug Name: N-Propyl-ETAV Drug Info
• Synonyms: N-Propyl-ETAV; CHEMBL494287

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 44568833
  TTD Drug ID: DMUTDNV

Molecule-Related Drug Atlas

Drug(s) Targeting Presynaptic density protein 95 (DLG4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tat-NR2B9c	DMD6AUX	Cerebrovascular ischaemia	8B1Z	Phase 3	[2]
2-Methyl-2,4-Pentanediol	DMD45CU	Discovery agent	N.A.	Investigative	[3]
Guanosine-5'-Monophosphate	DM3SLZK	Discovery agent	N.A.	Investigative	[3]
KSG-YEKLSSIESDV	DMPLFRC	Discovery agent	N.A.	Investigative	[1]
N-(3,4-Difluorophenyl)propyl-ETAV	DMF2D4O	Discovery agent	N.A.	Investigative	[1]
N-Phenylethyl-ETAV	DM1VSO9	Discovery agent	N.A.	Investigative	[1]
N-Cyclohexylmethyl-ETAV	DMIC8Z6	Discovery agent	N.A.	Investigative	[1]
FETAV	DMO1N2T	Discovery agent	N.A.	Investigative	[1]
N-Butyl-ETAV	DMY3HEF	Discovery agent	N.A.	Investigative	[1]
N-Methyl-ETAV	DMP1EF6	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Presynaptic density protein 95 (DLG4)	TT9PB26	DLG4_HUMAN	Inhibitor	[1]

References

• [1] Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem. 2008 Oct 23;51(20):6450-9.
• [2] Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain. Nature. 2012 Feb 29;483(7388):213-7.
• [3] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.