Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUVGMS)

Drug Name
MRG-110 Drug Info
Indication
Disease Entry ICD 11 Status REF
Heart failure BD10-BD13 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMUVGMS

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
microRNA hsa-miR-92 (MIR92) TTIXJ2S NOUNIPROTAC Inhibitor [2]

References

1 ClinicalTrials.gov (NCT03603431) Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MRG-110 Following Intradermal Injection in Healthy Volunteers. U.S. National Institutes of Health.
2 Efficiency and Target Derepression of Anti-miR-92a: Results of a First in Human Study. Nucleic Acid Ther. 2020 Dec;30(6):335-345.