Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUXEBQ)

• Drug Name: Polyamine Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Investigative	[1]

• Cross-matching ID:
  TTD Drug ID: DMUXEBQ
  VARIDT Drug ID: DR01251

Molecular Interaction Atlas of This Drug

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Lymphocyte activation antigen 4F2 (SLC3A2)	DT01CKS	4F2_HUMAN	Substrate	[2]

References

• [1] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
• [2] Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma.