Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV2XUM)

Drug Name
BRL50481 Drug Info
Synonyms BRL-50481; BRL 50481
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2921148
ChEBI ID
CHEBI:93472
CAS Number
CAS 433695-36-4
TTD Drug ID
DMV2XUM

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Phosphodiesterase 7B (PDE7B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PF-3557156 DMITYCN Pain MG30-MG3Z Discontinued in Phase 1 [3]
SCH51866 DMCWSJP Discovery agent N.A. Investigative [4]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 7B (PDE7B) TTWIEY9 PDE7B_HUMAN Inhibitor [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5154).
2 New classes of PDE7 inhibitors identified by a fission yeast-based HTS. J Biomol Screen. 2010 Apr;15(4):359-67.
3 Company report (Pfizer pipeline: October 28, 2008)
4 Identification of human PDE7B, a cAMP-specific phosphodiesterase. Biochem Biophys Res Commun. 2000 May 19;271(3):575-83.