Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMV319J)

Drug Name

RO-4905417 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Acute coronary syndrome	BA41	Phase 2	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

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Drug(s) Targeting P-selectin glycoprotein ligand 1 (SELPLG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AbGn-168	DMT6H3J	Allergy	4A80-4A85	Phase 2	[3]
Neihulizumab	DMUPZFO	Psoriatic arthritis	FA21	Phase 2	[4]
SelK2	DMM6B6E	Asthma	CA23	Phase 2	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
P-selectin glycoprotein ligand 1 (SELPLG)	TTS5K8U	SELPL_HUMAN	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT01245634) A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery. U.S. National Institutes of Health.
2	WO patent application no. 2013,0144,05, Methods.
3	Clinical pipeline report, company report or official report of Avarx.
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	Clinical pipeline report, company report or official report of Tetherex Pharmaceuticals