General Information of Drug (ID: DMV6FL8)

Drug Name
US8481733, 106 Drug Info
Synonyms SCHEMBL1128749; SCHEMBL1128751; CHEMBL2325938; BDBM98294; US8481733, 106
Cross-matching ID
PubChem CID
44468332
TTD Drug ID
DMV6FL8

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Patented Agent(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BDBM50379214 DMPOVZ6 N. A. N. A. Patented [2]
US8481733, 95 DM36R21 N. A. N. A. Patented [1]
US8481733, 118 DMZQIKL N. A. N. A. Patented [1]
PMID17280833C30 DMXHS4L Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Activated CDC42 kinase 1 (ACK-1) TTIET93 ACK1_HUMAN Inhibitor [1]

References

1 Substituted imidazopyr- and imidazotri-azines. US8481733.
2 Kinase modulators for the treatment of cancer. US9416123.
3 Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and prelimin... Bioorg Med Chem Lett. 2007 Apr 15;17(8):2305-9.