Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVD327)

Drug Name

AVI-7288 Drug Info

Indication

Disease Entry	ICD 11	Status	REF
Marburg virus infection	1D60.1	Phase 1	[1]

Cross-matching ID

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Marburg virus NP messenger RNA (MV NP mRNA)	TT1E5A4	NCAP_MABVM	Not Available	[2]

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References

1	ClinicalTrials.gov (NCT01566877) A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7288 in Healthy Adult Volunteers. U.S. National Institutes of Health.
2	AVI-7288 for Marburg Virus in Nonhuman Primates and Humans. N Engl J Med. 2015 Jul 23;373(4):339-48.