General Information of Drug (ID: DMVF2YH)

Drug Name
Antileukoprotease (ALP) Drug Info
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
TTD Drug ID
DMVF2YH

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Drug(s) Targeting Kallikrein-7 (KLK7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID23849879C3 DMUW3MT Discovery agent N.A. Investigative [2]
PMID25489658C4d DMWZJT0 Discovery agent N.A. Investigative [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Kallikrein-7 (KLK7) TTE6GTB KLK7_HUMAN Inhibitor [1]

References

1 Expression of the protease inhibitor antileukoprotease and the serine protease stratum corneum chymotryptic enzyme (SCCE) is coordinated in ovarian tumors. Int J Gynecol Cancer. 2001 Nov-Dec;11(6):454-61.
2 1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4547-51.
3 Toward the first class of suicide inhibitors of kallikreins involved in skin diseases. J Med Chem. 2015 Jan 22;58(2):598-612.