Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVJL8H)

Drug Name

cyclic CMP Drug Info

Synonyms

cytidine, cyclic 3',5'-(hydrogen phosphate)

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

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Drug(s) Targeting Hyperpolarization cyclic nucleotide-gated channel 2 (HCN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PIP2	DMOZV7N	Discovery agent	N.A.	Investigative	[3]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hyperpolarization cyclic nucleotide-gated channel 2 (HCN2)	TT9EUT4	HCN2_HUMAN	Activator	[2]

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References

1	cCMP and cUMP: emerging second messengers. Trends Biochem Sci. 2015 Jan;40(1):8-15.
2	Regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity by cCMP. J Biol Chem. 2012 Aug 3;287(32):26506-12.
3	Regulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2. J Gen Physiol. 2006 Nov;128(5):593-604.