Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVSI6R)

Drug Name
2-[(Dioxidophosphino)Oxy]Benzoate Drug Info
Synonyms
2-[(DIOXIDOPHOSPHINO)OXY]BENZOATE; 2-phosphooxybenzoate; 2-(phosphooxy)benzoate; AC1NR9RL; AC1O4QG1; 2-oxidophosphonoyloxybenzoate; 2-[(dioxidophosphanyl)oxy]benzoate; 2-[(Dioxidophosphoranyl)oxy]benzoate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
6398365
TTD Drug ID
DMVSI6R

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial DD-carboxypeptidase (Bact vanYB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cefalotin DMVYSLE Bacteremia 1A73 Approved [2]
B-Lactams DMR8YD6 Bacterial infection 1A00-1C4Z Approved [3]
Cephalosporin DM79XDW Bacterial infection 1A00-1C4Z Approved [4]
Cefotaxime DMEB837 Bacteremia 1A73 Approved [5]
TD-1792 DMGKBZH Skin infection 1F28-1G0Z Phase 3 [6]
Phenyl Boronic acid DMFZH49 Discovery agent N.A. Investigative [7]
Cephalosporin C DMYW3ZG Discovery agent N.A. Investigative [8]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [1]
D-Alanine DMVIDQL Discovery agent N.A. Investigative [1]
3-boronobenzoic acid DMRCJW0 Discovery agent N.A. Investigative [7]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial DD-carboxypeptidase (Bact vanYB) TTLP6GN VANY_ENTFA Inhibitor [1]

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2 Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry. 1995 Jul 25;34(29):9532-40.
3 Has nature already identified all useful antibacterial targets Curr Opin Microbiol. 2008 Oct;11(5):387-92.
4 A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1427-31.
5 Extended-spectrum cephalosporinases: structure, detection and epidemiology. Future Microbiol. 2007 Jun;2:297-307.
6 How many modes of action should an antibiotic have Curr Opin Pharmacol. 2008 Oct;8(5):564-73.
7 Synthesis and evaluation of 3-(dihydroxyboryl)benzoic acids as D,D-carboxypeptidase R39 inhibitors. J Med Chem. 2009 Oct 8;52(19):6097-106.
8 DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.