Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVWGM2)

Drug Name
GWTLNSAGYLLGPPPGFSPFR-CONH2 Drug Info
Synonyms
M35 Peptide; Galanin-(1-13)-bradykinin-(2-9)-amide; 142846-71-7; M-35; L-Argininamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-; M 35; Galanin(1-13)-bradykinin(2-9)amide; NCGC00167245-01
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
91934871
TTD Drug ID
DMVWGM2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Galanin receptor type 2 (GAL2-R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GwTLNSAGYLLGPHAVGNHRSFSDKNGLTS-CONH2 DMPIRE0 Discovery agent N.A. Investigative [1]
[Sar1Gly]GAL-B2 DMUI0XV Discovery agent N.A. Investigative [1]
(Sar)WTLNSAGYLLGPKK(Lys-lauroyl)K DMPZHIE Discovery agent N.A. Investigative [2]
GalB2 DMGX6UH Discovery agent N.A. Investigative [1]
(Sar)WTLNSAGYLLGPKK(Lys-octanoyl)K DMX3K4E Discovery agent N.A. Investigative [2]
(Sar)WTLNSAGYLLGPKK(Lys-decanoyl)K DMJL8SE Discovery agent N.A. Investigative [2]
(Sar)WTLNSAGYLLGPKK(Lys-MPEG4)K DMQIHZU Discovery agent N.A. Investigative [2]
[Sar1Ala]GAL-B2 DMUD0LA Discovery agent N.A. Investigative [1]
GWTLNSAGYLLGPHAV-NH2 DMZPRIG Discovery agent N.A. Investigative [3]
GWTLNSAGYLLGPrPKPQQwFwLL-CONH2 DM48AV3 Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Targeting Galanin receptor type 1 (GAL1-R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GwTLNSAGYLLGPHAVGNHRSFSDKNGLTS-CONH2 DMPIRE0 Discovery agent N.A. Investigative [1]
[Sar1Gly]GAL-B2 DMUI0XV Discovery agent N.A. Investigative [1]
(Sar)WTLNSAGYLLGPKK(Lys-lauroyl)K DMPZHIE Discovery agent N.A. Investigative [2]
GalB2 DMGX6UH Discovery agent N.A. Investigative [1]
(Sar)WTLNSAGYLLGPKK(Lys-octanoyl)K DMX3K4E Discovery agent N.A. Investigative [2]
(Sar)WTLNSAGYLLGPKK(Lys-decanoyl)K DMJL8SE Discovery agent N.A. Investigative [2]
(Sar)WTLNSAGYLLGPKK(Lys-MPEG4)K DMQIHZU Discovery agent N.A. Investigative [2]
[Sar1Ala]GAL-B2 DMUD0LA Discovery agent N.A. Investigative [1]
GWTLNSAGYLLGPHAV-NH2 DMZPRIG Discovery agent N.A. Investigative [3]
GWTLNSAGYLLGPrPKPQQwFwLL-CONH2 DM48AV3 Discovery agent N.A. Investigative [1]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Galanin receptor type 1 (GAL1-R) TTX3HNZ GALR1_HUMAN Inhibitor [1]
Galanin receptor type 2 (GAL2-R) TTBPW3J GALR2_HUMAN Inhibitor [1]

References

1 Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic de... J Med Chem. 2010 Feb 25;53(4):1871-5.
2 Structural requirements for a lipoamino acid in modulating the anticonvulsant activities of systemically active galanin analogues. J Med Chem. 2009 Mar 12;52(5):1310-6.
3 Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. J Med Chem. 2008 Dec 25;51(24):8038-47.