Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVYSAZ)

Drug Name

CRT-0004592 Drug Info

Synonyms

CRT-0066854; CRT-0099431; Protein kinase C iota inhibitors (cancer); PKCi inhibitors (cancer), CRT; Protein kinase C iota inhibitors (cancer), Cancer Research Technology

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]

Cross-matching ID

TTD Drug ID: DMVYSAZ

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Discontinued Drug(s)

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Drug(s) Targeting Protein kinase C iota (PRKCI)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ICA-1	DM1C4IG	Solid tumour/cancer	2A00-2F9Z	Terminated	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Protein kinase C iota (PRKCI)	TTWJTHX	KPCI_HUMAN	Inhibitor	[1]

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References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1490).
2	A novel PKC- inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma. Int J Biochem Cell Biol. 2011 May;43(5):784-94.