Details of the Drug-Related molecule(s) Interaction Atlas

NG7 Drug Info

3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide; 3-(2-(cyclopropanecarboxamido)thiazolo[5,4-b]pyridin-5-yl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide; HG-7-85-01; MLS003230942; SCHEMBL1696179; CHEMBL2148124; BDBM124970; SMR001913507; 1258391-13-7; US8765747, 2; NG7

Cross-matching ID

PubChem CID

51359962

TTD Drug ID

DMW1PL7

General Information of Drug (ID: DMW1PL7)

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Patented Agent(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Epithelial discoidin domain receptor 1 (DDR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
US9567304, Compound N-9	DMCGUNB	N. A.	N. A.	Patented	[2]
US9156852, 83	DM1K5T0	N. A.	N. A.	Patented	[3]
US9695118, 8	DMAD3VL	N. A.	N. A.	Patented	[4]
US9567304, Compound F-54	DM81MV6	N. A.	N. A.	Patented	[2]
VAPBGCRAUJRZPO-UHFFFAOYSA-N	DMOVEZF	N. A.	N. A.	Patented	[4]
BDBM50080408	DM4I829	N. A.	N. A.	Patented	[2]
US9695118, 4	DMZF3AQ	N. A.	N. A.	Patented	[4]
PMID23521020C7k	DMPCTED	Discovery agent	N.A.	Investigative	[5]
------------------------------------------------------------------------------------


⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Epithelial discoidin domain receptor 1 (DDR1)	TTI1FPZ	DDR1_HUMAN	Inhibitor	[1]

------------------------------------------------------------------------------------

References

1	Fused 2-aminothiazole compounds. US8765747.
2	Quinazolinedione derivative. US9567304.
3	Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases. US9156852.
4	Benzamide derivative. US9695118.
5	Discovery and optimization of 3-(2-(Pyrazolo[1,5-a]pyrimidin-6-yl)ethynyl)benzamides as novel selective and orally bioavailable discoidin domain receptor 1 (DDR1) inhibitors. J Med Chem. 2013 Apr 25;56(8):3281-95.