Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMW4JRY)

Drug Name
OBT076 Drug Info
Synonyms MEN1309
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 1 [1]
Cross-matching ID
TTD Drug ID
DMW4JRY

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lymphocyte antigen 75 (LY75) TTG180Q LY75_HUMAN Not Available [2]

References

1 ClinicalTrials.gov (NCT04064359) Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors and HER2-neg Breast Cancer. U.S. National Institutes of Health.
2 MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors. Mol Cancer Ther. 2019 Sep;18(9):1533-1543.